Have you tried reinstalling the wacom drivers? I’ve had issues getting the wacom to run after a fresh install, installing the new Wacom Feel Driver from their webseite that someone on the forum here had pointed out got it working for me.
I installed that, and the wacom pen app that comes with it is the only thing that registers the input when I calibrate the screen. Outside the calibration, it doesnt work. I believe that windows is supposed to have a pen option under device settings, but I dont have that. It may have a problem with windows? Im not sure.